Other major signs are a wide gap between the first and second toes short fourth and fifth rays of the feet and pes planus summary by bongers et al 2001.
Sandal gap toes and hypotonia.
A widely spaced gap between the first toe the great toe and the second toe.
1 2 more on sandal gap causes list.
Gap gap between 1st and 2nd toes gap between first and second toe increased space between first and second toes sandal gap between first and second toes wide space between rarediseases info nih gov low or weak muscle tone 0001252 neuroblastoma cancer of early nerve cells 0003006 otitis media middle ear infection 0000388 pes planus flat feet.
Pediatric onset pulmonary arterial hypertension may be seen in association with icpps kerstjens frederikse et al 2013 and levy et al 2016.
While this finding can occur as a familial trait when it occurs in constellation with other features of down s it supports the diagnosis.
While it can be a normal variant especially when it is the only finding it is also sometimes considered.
A sandal gap deformity also known as hallux varus is an imaging observation in antenatal ultrasound typically second trimester where there is an expanded first interspace i e.
3 causes of sandal gap.
Another physical finding in many infants with down s syndrome is an increased gap between the great and first toes.